Therapeutic effects of CSF1R-blocking antibodies in multiple myeloma

Our previous studies showed that macrophages (MФs), especially myeloma-associated MФs (MAMs) induce chemoresistance in human myeloma. Here we explored the potential of targeting MФs, by using colony-stimulating factor 1 receptor (CSF1R)-blocking mAbs, to treat myeloma. Our results showed that CSF1R...

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Foilsithe in:Leukemia
Main Authors: Wang, Qiang, Lu, Yong, Li, Rong, Jiang, Yuxue, Zheng, Yuhuan, Qian, Jianfei, Bi, Enguang, Zheng, Chengyun, Hou, Jian, Wang, Siqing, Yi, Qing
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927777/
https://ncbi.nlm.nih.gov/pubmed/28626216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.193
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