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Identification of DISE-inducing shRNAs by monitoring cellular responses
Off-target effects (OTE) are an undesired side effect of RNA interference (RNAi) caused by partial complementarity between the targeting siRNA and mRNAs other than the gene to be silenced. The death receptor CD95 and its ligand CD95L contain multiple sequences that when expressed as either si- or sh...
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| Veröffentlicht in: | Cell Cycle |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5927643/ https://ncbi.nlm.nih.gov/pubmed/29092660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1383576 |
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