Dectin-1/2–induced autocrine PGE(2) signaling licenses dendritic cells to prime Th2 responses

The molecular mechanisms through which dendritic cells (DCs) prime T helper 2 (Th2) responses, including those elicited by parasitic helminths, remain incompletely understood. Here, we report that soluble egg antigen (SEA) from Schistosoma mansoni, which is well known to drive potent Th2 responses,...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Kaisar, Maria M. M., Ritter, Manuel, del Fresno, Carlos, Jónasdóttir, Hulda S., van der Ham, Alwin J., Pelgrom, Leonard R., Schramm, Gabriele, Layland, Laura E., Sancho, David, Prazeres da Costa, Clarissa, Giera, Martin, Yazdanbakhsh, Maria, Everts, Bart
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927467/
https://ncbi.nlm.nih.gov/pubmed/29668708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005504
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