Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses

The propensity of helminths, such as schistosomes, to immunomodulate the host's immune system is an essential aspect of their survival. Previous research has demonstrated how soluble schistosomal egg antigens (SEA) dampen TLR-signaling during innate immune responses. We show here that the suppr...

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Bibliografiske detaljer
Main Authors: Ritter, Manuel, Gross, Olaf, Kays, Sarah, Ruland, Jürgen, Nimmerjahn, Falk, Saijo, Shinobu, Tschopp, Jürg, Layland, Laura E., Prazeres da Costa, Clarissa
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996650/
https://ncbi.nlm.nih.gov/pubmed/21059925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010337107
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