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The Role of Potassium in Inflammasome Activation by Bacteria

Many Gram-negative bacteria possess a type III secretion system (TTSS(¶)) that can activate the NLRC4 inflammasome, process caspase-1 and lead to secretion of mature IL-1β. This is dependent on the presence of intracellular flagellin. Previous reports have suggested that this activation is independe...

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Autori principali: Arlehamn, Cecilia S. Lindestam, Pétrilli, Virginie, Gross, Olaf, Tschopp, Jürg, Evans, Tom J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856258/
https://ncbi.nlm.nih.gov/pubmed/20097760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.067298
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