AhR activation increases IL-2 production by alloresponding CD4(+) T cells initiating the differentiation of mucosal-homing Tim3(+)Lag3(+) Tr1 cells

Activation of the aryl hydrocarbon receptor (AhR) by immunosuppressive ligands promotes the development of regulatory T (Treg) cells. Although AhR-induced Foxp3(+) Treg cells have been well studied, much less is known about the development and fate of AhR-induced Type 1 Treg (AhR-Tr1) cells. In the...

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Vydáno v:Eur J Immunol
Hlavní autoři: Ehrlich, Allison K., Pennington, Jamie M., Tilton, Susan, Wang, Xisheng, Marshall, Nikki B., Rohlman, Diana, Funatake, Castle, Punj, Sumit, O’Donnell, Edmond, Yu, Zhen, Kolluri, Siva K., Kerkvliet, Nancy I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927372/
https://ncbi.nlm.nih.gov/pubmed/28833046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747121
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