Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes

A defect in indoleamine 2,3-dioxygenase 1 (IDO1), which is responsible for immunoregulatory tryptophan catabolism, impairs development of immune tolerance to autoantigens in NOD mice, a model for human autoimmune type 1 diabetes (T1D). Whether IDO1 function is also defective in T1D is still unknown....

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Orabona, Ciriana, Mondanelli, Giada, Pallotta, Maria T., Carvalho, Agostinho, Albini, Elisa, Fallarino, Francesca, Vacca, Carmine, Volpi, Claudia, Belladonna, Maria L., Berioli, Maria G., Ceccarini, Giulia, Esposito, Susanna M.R., Scattoni, Raffaella, Verrotti, Alberto, Ferretti, Alessandra, De Giorgi, Giovanni, Toni, Sonia, Cappa, Marco, Matteoli, Maria C., Bianchi, Roberta, Matino, Davide, Iacono, Alberta, Puccetti, Matteo, Cunha, Cristina, Bicciato, Silvio, Antognelli, Cinzia, Talesa, Vincenzo N., Chatenoud, Lucienne, Fuchs, Dietmar, Pilotte, Luc, Van den Eynde, Benoît, Lemos, Manuel C., Romani, Luigina, Puccetti, Paolo, Grohmann, Ursula
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926942/
https://ncbi.nlm.nih.gov/pubmed/29563329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96244
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