Endothelial cell Pannexin1 modulates severity of ischemic stroke by regulating cerebral inflammation and myogenic tone

Ischemic stroke is a leading cause of morbidity and mortality in the US; however, there currently exists only one effective acute pharmacological therapeutic intervention. Purinergic signaling has been shown to regulate vascular function and pathological processes, including inflammation and arteria...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Good, Miranda E, Eucker, Stephanie A., Li, Jun, Bacon, Hannah M., Lang, Susan M., Butcher, Joshua T., Johnson, Tyler J., Gaykema, Ronald P., Patel, Manoj K., Zuo, Zhiyi, Isakson, Brant E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926909/
https://ncbi.nlm.nih.gov/pubmed/29563335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96272
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