Endothelial cell Pannexin1 modulates severity of ischemic stroke by regulating cerebral inflammation and myogenic tone

Ischemic stroke is a leading cause of morbidity and mortality in the US; however, there currently exists only one effective acute pharmacological therapeutic intervention. Purinergic signaling has been shown to regulate vascular function and pathological processes, including inflammation and arteria...

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Publicat a:JCI Insight
Autors principals: Good, Miranda E, Eucker, Stephanie A., Li, Jun, Bacon, Hannah M., Lang, Susan M., Butcher, Joshua T., Johnson, Tyler J., Gaykema, Ronald P., Patel, Manoj K., Zuo, Zhiyi, Isakson, Brant E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926909/
https://ncbi.nlm.nih.gov/pubmed/29563335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96272
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