Endothelial cell Pannexin1 modulates severity of ischemic stroke by regulating cerebral inflammation and myogenic tone

Ischemic stroke is a leading cause of morbidity and mortality in the US; however, there currently exists only one effective acute pharmacological therapeutic intervention. Purinergic signaling has been shown to regulate vascular function and pathological processes, including inflammation and arteria...

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Bibliografski detalji
Izdano u:JCI Insight
Glavni autori: Good, Miranda E, Eucker, Stephanie A., Li, Jun, Bacon, Hannah M., Lang, Susan M., Butcher, Joshua T., Johnson, Tyler J., Gaykema, Ronald P., Patel, Manoj K., Zuo, Zhiyi, Isakson, Brant E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926909/
https://ncbi.nlm.nih.gov/pubmed/29563335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96272
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