Phosphorylation of Fas‐associated Death Domain Contributes to Enhancement of Etoposide‐induced Apoptosis in Prostate Cancer Cells

Fas‐associated death domain (FADD) plays an important role as an adapter molecule in Fas (CD95/APO‐l)‐mediated apoptosis and contributes to anticancer drug‐induced cytotoxicity. We treated three human prostate cancer cell lines with etoposide, a toposiomerase II inhibitor with activity against vario...

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Vydáno v:Jpn J Cancer Res
Hlavní autoři: Shimada, Keiji, Nakamura, Mitsutoshi, Ishida, Eiwa, Kishi, Munehiro, Yonehara, Shin, Konishi, Noboru
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2002
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926882/
https://ncbi.nlm.nih.gov/pubmed/12417047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb01219.x
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