c-Jun NH(2) Terminal Kinase Activation and Decreased Expression of Mitogen-Activated Protein Kinase Phosphatase-1 Play Important Roles in Invasion and Angiogenesis of Urothelial Carcinomas

We here examined whether c-Jun NH(2) terminal kinase (JNK) might be involved in the progression of urothelial carcinomas. In vitro and in vivo invasion assays using Matrigel and chick embryo chorioallantoic membrane approaches showed constitutive activation of JNK to significantly increase two proce...

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Bibliographic Details
Main Authors: Shimada, Keiji, Nakamura, Mitsutoshi, Ishida, Eiwa, Higuchi, Tomonori, Tanaka, Motoyoshi, Ota, Ichiro, Konishi, Noboru
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2007
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959476/
https://ncbi.nlm.nih.gov/pubmed/17690186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070010
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