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c-Jun NH(2) Terminal Kinase Activation and Decreased Expression of Mitogen-Activated Protein Kinase Phosphatase-1 Play Important Roles in Invasion and Angiogenesis of Urothelial Carcinomas

We here examined whether c-Jun NH(2) terminal kinase (JNK) might be involved in the progression of urothelial carcinomas. In vitro and in vivo invasion assays using Matrigel and chick embryo chorioallantoic membrane approaches showed constitutive activation of JNK to significantly increase two proce...

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Main Authors: Shimada, Keiji, Nakamura, Mitsutoshi, Ishida, Eiwa, Higuchi, Tomonori, Tanaka, Motoyoshi, Ota, Ichiro, Konishi, Noboru
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959476/
https://ncbi.nlm.nih.gov/pubmed/17690186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070010
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