Enhancement of in vivo Antitumor Activity of a Novel Antimitotic 1‐Phenylpropenone Derivative, AM‐132, by Tumor Necrosis Factor‐cc or Interleukin‐6

TK5048 and its derivatives, AM‐132, AM‐138, and AM‐97, are recently developed antimitotic (AM) compounds. These 1‐phenylpropenone derivatives induce cell cycle arrest at the G2/M phase of the cell cycle. TK5048 inhibited tubulin polymerization in human lung cancer PC‐14 cells in a concentration‐depe...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Tatsumi, Yasuaki, Arioka, Hitoshi, Ikeda, Shun‐ichi, Fukumoto, Hisao, Miyamoto, Ken‐ichi, Fukuoka, Kazuya, Ohe, Yuichiro, Saijo, Nagahiro, Nishio, Kazuto
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926787/
https://ncbi.nlm.nih.gov/pubmed/11473728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb01160.x
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