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Hypophosphorylation of Topoisomerase IIα in Etoposide (VP‐16)‐resistant Human Carcinoma Cell Lines Associated with Carboxy‐terminal Truncation
Topoisomerase Ilα is a target for many chemotherapeutic agents in clinical use. To define mechanisms of resistance and regions crucial for the function of topoisomerase IIα, drug‐resistant cell lines have been isolated following exposure to topoisomerase II poisons. Two resistant sublines, T47D‐VP a...
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| Izdano u: | Jpn J Cancer Res |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Publishing Ltd
2001
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5926775/ https://ncbi.nlm.nih.gov/pubmed/11473732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb01164.x |
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