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Role of Nitric Oxide in the Chemistry and Anticancer Activity of Etoposide (VP-16,213)

Originally identified as an innate cytotoxin, nitric oxide (•NO) formation in tumors can influence chemotherapy and exacerbate cancer progression. Here, we examined the hypothesis that •NO generation contributes to cancer cell drug resistance towards the widely used anticancer drug Etoposide (VP-16)...

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Dettagli Bibliografici
Autori principali: Sinha, Birandra K., Bhattacharjee, Suchandra, Chatterjee, Saurabh, Jiang, JinJie, Motten, Ann G., Kumar, Ashutosh, Espey, Michael Graham, Mason, Ronald P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697829/
https://ncbi.nlm.nih.gov/pubmed/23402364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300480q
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