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Nitric oxide inhibits ATPase activity and induces resistance to topoisomerase II-poisons in human MCF-7 breast tumor cells
BACKGROUND: Topoisomerase poisons are important drugs for the management of human malignancies. Nitric oxide ((•)NO), a physiological signaling molecule, induces nitrosylation (or nitrosation) of many cellular proteins containing cysteine thiol groups, altering their cellular functions. Topoisomeras...
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| Publicado no: | Biochem Biophys Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5614683/ https://ncbi.nlm.nih.gov/pubmed/28955753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2017.04.011 |
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