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Carboxy-Terminal Truncations Modify the Outer Pore Vestibule of Muscle Chloride Channels

Mammalian ClC-type chloride channels have large cytoplasmic carboxy-terminal domains whose function is still insufficiently understood. We investigated the role of the distal part of the carboxy-terminus of the muscle isoform ClC-1 by constructing and functionally evaluating two truncation mutants,...

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Autores principales: Hebeisen, Simon, Fahlke, Christoph
Formato: Artigo
Lenguaje:Inglês
Publicado: Biophysical Society 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366675/
https://ncbi.nlm.nih.gov/pubmed/15980168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.056093
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