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Gating of human ClC-2 chloride channels and regulation by carboxy-terminal domains
Eukaryotic ClC channels are dimeric proteins with each subunit forming an individual protopore. Single protopores are gated by a fast gate, whereas the slow gate is assumed to control both protopores through a cooperative movement of the two carboxy-terminal domains. We here study the role of the ca...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2655382/ https://ncbi.nlm.nih.gov/pubmed/18801843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.158097 |
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