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Anion- and Proton-Dependent Gating of ClC-4 Anion/Proton Transporter under Uncoupling Conditions

ClC-4 is a secondary active transporter that exchanges Cl(−) ions and H(+) with a 2:1 stoichiometry. In external SCN(−), ClC-4 becomes uncoupled and transports anions with high unitary transport rate. Upon voltage steps, the number of active transporters varies in a time-dependent manner, resembling...

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Hlavní autoři: Orhan, Gökce, Fahlke, Christoph, Alekov, Alexi K.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043216/
https://ncbi.nlm.nih.gov/pubmed/21354396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.01.045
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