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Anion- and Proton-Dependent Gating of ClC-4 Anion/Proton Transporter under Uncoupling Conditions
ClC-4 is a secondary active transporter that exchanges Cl(−) ions and H(+) with a 2:1 stoichiometry. In external SCN(−), ClC-4 becomes uncoupled and transports anions with high unitary transport rate. Upon voltage steps, the number of active transporters varies in a time-dependent manner, resembling...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3043216/ https://ncbi.nlm.nih.gov/pubmed/21354396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.01.045 |
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