X‐Irradiation Induces Up‐regulation of ATM Gene Expression in Wild‐type Lymphoblastoid Cell Lines, but Not in Their Heterozygous or Homozygous Ataxia‐telangiectasia Counterparts

Ataxia‐telangiectasia (AT) is an autosomal recessive disease. The relevant gene has been cloned and designated ATM. We studied the expression of both ATM mRNA and the ATM protein in unirradi‐ated and X‐irradiated EBV (Epstein‐Barr virus)‐transformed lymphoblastoid cell lines (LCLs) derived from dono...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Hirai, Yuko, Hayashi, Tomonori, Kubo, Yoshiko, Hoki, Yuko, Arita, Izumi, Tatsumi, Kouichi, Seyama, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926759/
https://ncbi.nlm.nih.gov/pubmed/11429062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb01152.x
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