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High Frequency of Deletions at the Hypoxanthine‐guanine Phosphoribosyl‐transferase Locus in an Ataxia‐telangiectasia Lymphoblastoid Cell Line Irradiated with y‐Rays

The molecular nature of y‐ray‐induced mutations at the hypoxanthine‐guanine phosphoribosyl‐transferase (HPRT) locus in an ataxia‐telangiectasia (A‐T) lymphoblastoid cell line was investigated. Twelve of 15 y‐ray‐induced HPRT‐deficient mutants showed deletions. Eight of them had lost the entire HPRT...

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Detaylı Bibliyografya
Yayımlandı:Jpn J Cancer Res
Asıl Yazarlar: Tachibana, Akira, Tatsumi, Kouichi, Furuno‐Fukushi, Ikuko, Sasaki, Masao S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2001
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926665/
https://ncbi.nlm.nih.gov/pubmed/11714443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb02139.x
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