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Activation of Variants of Hypoxanthine-Guanine Phosphoribosyl Transferase by the Normal Enzyme

Deficient hypoxanthine-guanine phosphoribosyl transferase (HGPRT; EC 2.4.2.8) enzymes from erythrocytes of patients with hyperuricemia and with the Lesch-Nyhan syndrome migrate 15% faster in polyacrylamide gel disc electrophoresis than the normal enzyme. A half-sister of two males with partial defic...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Bakay, Bohdan, Nyhan, William L.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1972
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426979/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4341698/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.9.2523
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