Activation of Variants of Hypoxanthine-Guanine Phosphoribosyl Transferase by the Normal Enzyme
Deficient hypoxanthine-guanine phosphoribosyl transferase (HGPRT; EC 2.4.2.8) enzymes from erythrocytes of patients with hyperuricemia and with the Lesch-Nyhan syndrome migrate 15% faster in polyacrylamide gel disc electrophoresis than the normal enzyme. A half-sister of two males with partial defic...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1972
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426979/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4341698/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.9.2523 |
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