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Dietary-Induced Variation of Hypoxanthine-Guanine Phosphoribosyl Transferase Activity in Patients with the Lesch-Nyhan Syndrome

We have studied three patients with the Lesch-Nyhan syndrome to assess the effect of dietary purines on erythrocyte hypoxanthine-guanine phosphoribosyltransferase (HGPRT) activity. During dietary purine restriction HGPRT activity rose in all three patients; resumption of normal dietary purine intake...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Arnold, William J., Kelley, William N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4693659/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107263
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