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Dietary-Induced Variation of Hypoxanthine-Guanine Phosphoribosyl Transferase Activity in Patients with the Lesch-Nyhan Syndrome

We have studied three patients with the Lesch-Nyhan syndrome to assess the effect of dietary purines on erythrocyte hypoxanthine-guanine phosphoribosyltransferase (HGPRT) activity. During dietary purine restriction HGPRT activity rose in all three patients; resumption of normal dietary purine intake...

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Autors principals: Arnold, William J., Kelley, William N.
Format: Artigo
Idioma:Inglês
Publicat: 1973
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC302346/
https://ncbi.nlm.nih.gov/pubmed/4693659
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