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Contribution of Caspase‐3 Differs by p53 Status in Apoptosis Induced by X‐Irradiation

We investigated the effect of p53 status on involvement of caspase‐3 activation in cell death induced by X‐irradiation, using rat embryonic fibroblasts (REFs) transduced with a temperature‐sensitive mutant (mt) p53 gene. Cells with wild‐type (wt) p53 showed greater resistance to X‐irradiation than c...

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Publicat a:Jpn J Cancer Res
Autors principals: Kobayashi, Daisuke, Tokino, Takashi, Watanabe, Naoki
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926727/
https://ncbi.nlm.nih.gov/pubmed/11346471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb01118.x
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