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Augmented Adriamycin Sensitivity in Cells Transduced with an Antisense Tumor Necrosis Factor Gene Is Mediated by Caspase‐3 Downstream from Reactive Oxygen Species

While transduction of an antisense tumor necrosis factor (TNF) gene sequence can augment the cytotoxicity of adriamycin (ADM) in human cancer cells, the specific effect of introducing this sequence on the signal transduction pathway leading to cell death remains unclear. In ADM‐resistant pancreatic...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Sasaki, Masahiro, Kobayashi, Daisuke, Watanabe, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926847/
https://ncbi.nlm.nih.gov/pubmed/11572767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb01189.x
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