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Contribution of Caspase‐3 Differs by p53 Status in Apoptosis Induced by X‐Irradiation

We investigated the effect of p53 status on involvement of caspase‐3 activation in cell death induced by X‐irradiation, using rat embryonic fibroblasts (REFs) transduced with a temperature‐sensitive mutant (mt) p53 gene. Cells with wild‐type (wt) p53 showed greater resistance to X‐irradiation than c...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Kobayashi, Daisuke, Tokino, Takashi, Watanabe, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926727/
https://ncbi.nlm.nih.gov/pubmed/11346471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb01118.x
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