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Paclitaxel and SN‐38 Overcome Cisplatin Resistance of Ovarian Cancer Cell Lines by Down‐regulating the Influx and Efflux System of Cisplatin

Cisplatin (DDP) is one of the key drugs used to treat patients with ovarian cancer, although resistance to DDP can occur. Paclitaxel and SN‐38 (an active metabolite of irinotecan (CPT‐11)) are two drugs that are effective in patients with DDP‐resistant ovarian cancer. To study how these drugs may ov...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Jpn J Cancer Res
Hauptverfasser: Komuro, Yuuki, Udagawa, Yasuhiro, Susumu, Nobuyuki, Aoki, Daisuke, Kubota, Tetsuro, Nozawa, Shiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926666/
https://ncbi.nlm.nih.gov/pubmed/11714450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb02146.x
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