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Paclitaxel and SN‐38 Overcome Cisplatin Resistance of Ovarian Cancer Cell Lines by Down‐regulating the Influx and Efflux System of Cisplatin

Cisplatin (DDP) is one of the key drugs used to treat patients with ovarian cancer, although resistance to DDP can occur. Paclitaxel and SN‐38 (an active metabolite of irinotecan (CPT‐11)) are two drugs that are effective in patients with DDP‐resistant ovarian cancer. To study how these drugs may ov...

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Bibliografiske detaljer
Udgivet i:Jpn J Cancer Res
Main Authors: Komuro, Yuuki, Udagawa, Yasuhiro, Susumu, Nobuyuki, Aoki, Daisuke, Kubota, Tetsuro, Nozawa, Shiro
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926666/
https://ncbi.nlm.nih.gov/pubmed/11714450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb02146.x
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