Schedule‐dependent Interactions between Raltitrexed and Cisplatin in Human Carcinoma Cell Lines in vitro

Raltitrexed (‘Tomudex”) is a new anticancer agent which inhibits thymidylate synthase. To provide a rational basis for clinical trial design of the combination of raltitrexed and cisplatin, we studied the cytotoxic effects of this combination using various schedules in vitro and four human colon can...

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Vydáno v:Jpn J Cancer Res
Hlavní autoři: Kano, Yasuhiko, Akutsu, Miyuki, Suzuki, Kenichi, Yazawa, Yasuo, Tsunoda, Saburo
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2000
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926465/
https://ncbi.nlm.nih.gov/pubmed/10804291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00962.x
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