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Schedule‐dependent Interactions between Raltitrexed and Cisplatin in Human Carcinoma Cell Lines in vitro

Raltitrexed (‘Tomudex”) is a new anticancer agent which inhibits thymidylate synthase. To provide a rational basis for clinical trial design of the combination of raltitrexed and cisplatin, we studied the cytotoxic effects of this combination using various schedules in vitro and four human colon can...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Kano, Yasuhiko, Akutsu, Miyuki, Suzuki, Kenichi, Yazawa, Yasuo, Tsunoda, Saburo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926465/
https://ncbi.nlm.nih.gov/pubmed/10804291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00962.x
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