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Schedule‐dependent Interactions between Raltitrexed and Cisplatin in Human Carcinoma Cell Lines in vitro

Raltitrexed (‘Tomudex”) is a new anticancer agent which inhibits thymidylate synthase. To provide a rational basis for clinical trial design of the combination of raltitrexed and cisplatin, we studied the cytotoxic effects of this combination using various schedules in vitro and four human colon can...

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Dettagli Bibliografici
Pubblicato in:Jpn J Cancer Res
Autori principali: Kano, Yasuhiko, Akutsu, Miyuki, Suzuki, Kenichi, Yazawa, Yasuo, Tsunoda, Saburo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926465/
https://ncbi.nlm.nih.gov/pubmed/10804291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00962.x
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