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Schedule‐dependent Interactions between Raltitrexed and Cisplatin in Human Carcinoma Cell Lines in vitro

Raltitrexed (‘Tomudex”) is a new anticancer agent which inhibits thymidylate synthase. To provide a rational basis for clinical trial design of the combination of raltitrexed and cisplatin, we studied the cytotoxic effects of this combination using various schedules in vitro and four human colon can...

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Publicat a:Jpn J Cancer Res
Autors principals: Kano, Yasuhiko, Akutsu, Miyuki, Suzuki, Kenichi, Yazawa, Yasuo, Tsunoda, Saburo
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926465/
https://ncbi.nlm.nih.gov/pubmed/10804291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00962.x
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