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Chemoprevention by Nimesulide, a Selective Cyclooxygenase‐2 Inhibitor, of 2‐Amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP)‐induced Mammary Gland Carcinogenesis in Rats

Breast cancer is common in women all over the world, and exploration of chemopreventive approaches to this cancer is very important. Nimesulide, a selective inhibitor of cyclooxygenase‐2 (COX‐2), is a good candidate as a chemopreventive agent with low toxicity. We examined its effects on mammary tum...

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Détails bibliographiques
Publié dans:Jpn J Cancer Res
Auteurs principaux: Nakatsugi, Seiichi, Ohta, Toshihisa, Kawamori, Toshihiko, Mutoh, Michihiro, Tanigawa, Tetsuya, Watanabe, Kouji, Sugie, Shigeyuki, Sugimura, Takashi, Wakabayashi, Keiji
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926448/
https://ncbi.nlm.nih.gov/pubmed/11011115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb01030.x
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