Suppression by Flavonoids of Cyclooxygenase‐2 Promoter‐dependent Transcriptional Activity in Colon Cancer Cells: Structure‐Activity Relationship

Cyclooxygenase‐2 (COX‐2) plays an important role in carcinogenesis. Investigation of the suppressive action of twelve flavonoids of different chemical classes on the transcriptional activity of the COX‐2 gene in human colon cancer DLD‐1 cells using a reporter gene assay have revealed quercetin to be...

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Publicat a:Jpn J Cancer Res
Autors principals: Mutoh, Michihiro, Takahashi, Mami, Fukuda, Kazunori, Komatsu, Hajime, Enya, Takeji, Matsushima‐Hibiya, Yuko, Mutoh, Hiroshi, Sugimura, Takashi, Wakabayashi, Keiji
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2000
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926411/
https://ncbi.nlm.nih.gov/pubmed/10920275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb01000.x
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