Suppression by Flavonoids of Cyclooxygenase‐2 Promoter‐dependent Transcriptional Activity in Colon Cancer Cells: Structure‐Activity Relationship

Cyclooxygenase‐2 (COX‐2) plays an important role in carcinogenesis. Investigation of the suppressive action of twelve flavonoids of different chemical classes on the transcriptional activity of the COX‐2 gene in human colon cancer DLD‐1 cells using a reporter gene assay have revealed quercetin to be...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Mutoh, Michihiro, Takahashi, Mami, Fukuda, Kazunori, Komatsu, Hajime, Enya, Takeji, Matsushima‐Hibiya, Yuko, Mutoh, Hiroshi, Sugimura, Takashi, Wakabayashi, Keiji
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2000
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926411/
https://ncbi.nlm.nih.gov/pubmed/10920275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb01000.x
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