Suppression of Intestinal Polyp Development by Nimesulide, a Selective Cyclooxygenase‐2 Inhibitor, in Min Mice

Nonsteroidal anti‐inflammatory drugs (NSAIDs) suppress colon carcinogenesis in man and experimental animals. However, conventional NSAIDs inhibit both cyclooxygenase (COX) isoforms, COX‐1 and COX‐2, and cause gastrointestinal side‐effects. Nimesulide, a selective inhibitor of COX‐2, is much less ulc...

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Bibliografiska uppgifter
I publikationen:Jpn J Cancer Res
Huvudupphovsmän: Nakatsugi, Seiichi, Fukutake, Masato, Takahashi, Mami, Fukuda, Kazunori, Isoi, Takashi, Taniguchi, Yasuaki, Sugimura, Takashi, Wakabayashi, Keiji
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 1997
Ämnen:
Rapid Communication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921349/
https://ncbi.nlm.nih.gov/pubmed/9473726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00337.x
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