Suppression of Intestinal Polyp Development by Nimesulide, a Selective Cyclooxygenase‐2 Inhibitor, in Min Mice

Nonsteroidal anti‐inflammatory drugs (NSAIDs) suppress colon carcinogenesis in man and experimental animals. However, conventional NSAIDs inhibit both cyclooxygenase (COX) isoforms, COX‐1 and COX‐2, and cause gastrointestinal side‐effects. Nimesulide, a selective inhibitor of COX‐2, is much less ulc...

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Bibliografische gegevens
Gepubliceerd in:Jpn J Cancer Res
Hoofdauteurs: Nakatsugi, Seiichi, Fukutake, Masato, Takahashi, Mami, Fukuda, Kazunori, Isoi, Takashi, Taniguchi, Yasuaki, Sugimura, Takashi, Wakabayashi, Keiji
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 1997
Onderwerpen:
Rapid Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921349/
https://ncbi.nlm.nih.gov/pubmed/9473726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00337.x
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