Suppression of Intestinal Polyp Development by Nimesulide, a Selective Cyclooxygenase‐2 Inhibitor, in Min Mice

Nonsteroidal anti‐inflammatory drugs (NSAIDs) suppress colon carcinogenesis in man and experimental animals. However, conventional NSAIDs inhibit both cyclooxygenase (COX) isoforms, COX‐1 and COX‐2, and cause gastrointestinal side‐effects. Nimesulide, a selective inhibitor of COX‐2, is much less ulc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Jpn J Cancer Res
Hauptverfasser: Nakatsugi, Seiichi, Fukutake, Masato, Takahashi, Mami, Fukuda, Kazunori, Isoi, Takashi, Taniguchi, Yasuaki, Sugimura, Takashi, Wakabayashi, Keiji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 1997
Schlagworte:
Rapid Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921349/
https://ncbi.nlm.nih.gov/pubmed/9473726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00337.x
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