Suppression of Intestinal Polyp Development by Nimesulide, a Selective Cyclooxygenase‐2 Inhibitor, in Min Mice

Nonsteroidal anti‐inflammatory drugs (NSAIDs) suppress colon carcinogenesis in man and experimental animals. However, conventional NSAIDs inhibit both cyclooxygenase (COX) isoforms, COX‐1 and COX‐2, and cause gastrointestinal side‐effects. Nimesulide, a selective inhibitor of COX‐2, is much less ulc...

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Detalles Bibliográficos
Publicado en:Jpn J Cancer Res
Autores principales: Nakatsugi, Seiichi, Fukutake, Masato, Takahashi, Mami, Fukuda, Kazunori, Isoi, Takashi, Taniguchi, Yasuaki, Sugimura, Takashi, Wakabayashi, Keiji
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 1997
Materias:
Rapid Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921349/
https://ncbi.nlm.nih.gov/pubmed/9473726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00337.x
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