Suppression of Intestinal Polyp Development by Nimesulide, a Selective Cyclooxygenase‐2 Inhibitor, in Min Mice

Nonsteroidal anti‐inflammatory drugs (NSAIDs) suppress colon carcinogenesis in man and experimental animals. However, conventional NSAIDs inhibit both cyclooxygenase (COX) isoforms, COX‐1 and COX‐2, and cause gastrointestinal side‐effects. Nimesulide, a selective inhibitor of COX‐2, is much less ulc...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Nakatsugi, Seiichi, Fukutake, Masato, Takahashi, Mami, Fukuda, Kazunori, Isoi, Takashi, Taniguchi, Yasuaki, Sugimura, Takashi, Wakabayashi, Keiji
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1997
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921349/
https://ncbi.nlm.nih.gov/pubmed/9473726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00337.x
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