TZT‐1027, an Antimicrotubule Agent, Attacks Tumor Vasculature and Induces Tumor Cell Death

TZT‐1027, a dolastatin 10 derivative, is an antimicrotubule agent with potent antitumor activity both in vitro and in vivo. In this study, we performed biochemical and histopathological examinations, and evaluated TZT‐1027‐induced tumoral vascular collapse and tumor cell death in an advanced tumor m...

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Vydáno v:Jpn J Cancer Res
Hlavní autoři: Otani, Masashi, Natsume, Tsugitaka, Watanabe, Jun‐ichi, Kobayashi, Motohiro, Murakoshi, Masanori, Mikami, Takashi, Nakayama, Takaharu
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2000
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926421/
https://ncbi.nlm.nih.gov/pubmed/10965026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb01022.x
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