TZT‐1027, an Antimicrotubule Agent, Attacks Tumor Vasculature and Induces Tumor Cell Death

TZT‐1027, a dolastatin 10 derivative, is an antimicrotubule agent with potent antitumor activity both in vitro and in vivo. In this study, we performed biochemical and histopathological examinations, and evaluated TZT‐1027‐induced tumoral vascular collapse and tumor cell death in an advanced tumor m...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Otani, Masashi, Natsume, Tsugitaka, Watanabe, Jun‐ichi, Kobayashi, Motohiro, Murakoshi, Masanori, Mikami, Takashi, Nakayama, Takaharu
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2000
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926421/
https://ncbi.nlm.nih.gov/pubmed/10965026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb01022.x
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