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Characterization of the Interaction of TZT‐1027, a Potent Antitumor Agent, with Tubulin
TZT‐1027, a derivative of dolastatin 10 isolated from the Indian Ocean sea hare Dolabella auricularia in 1987 by Pettit et al., is a potent antimicrotubule agent. We have compared the activity of TZT‐1027 with that of dolastatin 10 as well as the vinca alkaloids vinblastine (VLB), vincristine (VCR)...
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| Publicado no: | Jpn J Cancer Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5926414/ https://ncbi.nlm.nih.gov/pubmed/10920282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb01007.x |
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