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MDM2 Overexpression with Alteration of the p53 Protein and Gene Status in Oral Carcinogenesis
In this study, to better understand the mechanism of oral squamous cell carcinoma (SCC) carcinogenesis, alterations of the p53 gene and overexpression of MDM2 and p53 were analyzed in 38 oral SCC samples. Twelve of the 38 specimens revealed mutant‐type p53. Moreover, coexpression of MDM2 and p53 was...
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| Veröffentlicht in: | Jpn J Cancer Res |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5926374/ https://ncbi.nlm.nih.gov/pubmed/10835493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00972.x |
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