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MDM2 Overexpression with Alteration of the p53 Protein and Gene Status in Oral Carcinogenesis

In this study, to better understand the mechanism of oral squamous cell carcinoma (SCC) carcinogenesis, alterations of the p53 gene and overexpression of MDM2 and p53 were analyzed in 38 oral SCC samples. Twelve of the 38 specimens revealed mutant‐type p53. Moreover, coexpression of MDM2 and p53 was...

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Bibliografiska uppgifter
I publikationen:Jpn J Cancer Res
Huvudupphovsmän: Li, Xiao‐Jun, Murai, Mutsuhiko, Koyama, Takashi, Li, Xiao‐Jin, Wang, Dong‐Yu, Hashimoto, Kenji
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2000
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926374/
https://ncbi.nlm.nih.gov/pubmed/10835493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00972.x
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