Increased Frequencies of Gene and Chromosome Mutations after X‐Irradiation in Mouse Embryonal Carcinoma Cells Transfected with the bcl‐2 Gene

Preimplantation stage mouse embryos are known to be highly sensitive to the killing effect of DNA damaging agents such as radiation. Interestingly, however, this stage of development is well protected from radiation induction of malformation and carcinogenesis in postnatal life. In recent years, it...

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Publicat a:Jpn J Cancer Res
Autors principals: Taga, Masataka, Shiraishi, Kazunori, Shimura, Tsutomu, Uematsu, Norio, Oshimura, Mitsuo, Niwa, Ohtsura
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2000
Matèries:
Rapid Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926261/
https://ncbi.nlm.nih.gov/pubmed/11050469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00876.x
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