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Studies of Tumor Suppressor Genes via Chromosome Engineering

The development and progression of malignant tumors likely result from consecutive accumulation of genetic alterations, including dysfunctional tumor suppressor genes. However, the signaling mechanisms that underlie the development of tumors have not yet been completely elucidated. Discovery of nove...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Kugoh, Hiroyuki, Ohira, Takahito, Oshimura, Mitsuo
Format: Artigo
Language:Inglês
Published: MDPI 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728451/
https://ncbi.nlm.nih.gov/pubmed/26729168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers8010004
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