miR-19b regulates hTERT mRNA expression through targeting PITX1 mRNA in melanoma cells

Human telomerase reverse transcriptase (hTERT) plays a crucial role in cancer development. We previously identified paired-like homeodomain1 (PITX1) as an hTERT suppressor gene. However, the underlying mechanisms that are involved in the regulation of PITX1 remain unknown. Here, we report that the m...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Ohira, Takahito, Naohiro, Sunamura, Nakayama, Yuji, Osaki, Mitsuhiko, Okada, Futoshi, Oshimura, Mitsuo, Kugoh, Hiroyuki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314654/
https://ncbi.nlm.nih.gov/pubmed/25643913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08201
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