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Transduction of a Fiber‐mutant Adenovirus for the HSVtk Gene Highly Augments the Cytopathic Effect towards Gliomas
Suicide gene therapy utilizing the herpes simplex thymidine kinase (HSVtk)/ganciclovir (GCV) system has been performed to kill cancer cells. However, the low transduction efficiency of HSVtk gene into cancer cells critically limits its efficacy in cancer treatment in clinical situations. To improve...
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| Veröffentlicht in: | Jpn J Cancer Res |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5926260/ https://ncbi.nlm.nih.gov/pubmed/11050474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00881.x |
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