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A chimeric adenovirus with an Ad 3 fiber knob modification augments glioma virotherapy
BACKGROUND: Malignant gliomas remain refractory to treatment despite advances in chemotherapy and surgical techniques. Viral vectors developed to treat gliomas have had low transduction capabilities, limiting their use. Gliomas over-express CD46, CD80, and CD86, all of which bind adenovirus serotype...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2793323/ https://ncbi.nlm.nih.gov/pubmed/19688792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.1385 |
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