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LOW-DOSE RADIATION ENHANCES SURVIVIN MEDIATED VIROTHERAPY AGAINST MALIGNANT GLIOMA STEM CELLS

To improve the efficacy and selectivity of virotherapy for malignant glioma, we designed a strategy to amplify adenoviral replication in conjunction with radiotherapy using a radio-inducible promoter. First, we compared the radiation inducible activity of FLT-1, VEGF, DR5, Cox2, and survivin. We the...

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Detalhes bibliográficos
Main Authors: Nandi, Suvobroto, Ulasov, Ilya V., Tyler, Matthew, Sugihara, Adam Quasar, Molinero, Luciana, Han, Yu, Zhu, Zeng B., Lesniak., Maciej S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553687/
https://ncbi.nlm.nih.gov/pubmed/18632631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6441
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