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Immunohistochemical Detection of Carcinogen‐DNA Adducts in Normal Human Prostate Tissues Transplanted into the Subcutis of Athymic Nude Mice: Results with 2‐Amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP) and 3,2′‐Dimethyl‐4‐aminobiphenyl (DMAB) and Relation to Cytochrome P450s and N‐Acetyltransferase Activity
Human prostate tissue transplanted into nude mice was examined immunohistochemically for DNA adducts formed after administration of 3,2′‐dimethyl‐4‐aminobiphenyl (DMAB) or 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP). Positive staining for DMAB‐ or PhIP‐DNA adducts was evident in 70–95% of...
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| Gepubliceerd in: | Jpn J Cancer Res |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Blackwell Publishing Ltd
2000
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5926232/ https://ncbi.nlm.nih.gov/pubmed/10744044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00859.x |
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