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Immunohistochemical Detection of Carcinogen‐DNA Adducts in Normal Human Prostate Tissues Transplanted into the Subcutis of Athymic Nude Mice: Results with 2‐Amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP) and 3,2′‐Dimethyl‐4‐aminobiphenyl (DMAB) and Relation to Cytochrome P450s and N‐Acetyltransferase Activity

Human prostate tissue transplanted into nude mice was examined immunohistochemically for DNA adducts formed after administration of 3,2′‐dimethyl‐4‐aminobiphenyl (DMAB) or 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP). Positive staining for DMAB‐ or PhIP‐DNA adducts was evident in 70–95% of...

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Bibliografische gegevens
Gepubliceerd in:Jpn J Cancer Res
Hoofdauteurs: Cui, Lin, Takahashi, Satoru, Tada, Mariko, Kato, Koji, Yamada, Yasuyuki, Kohri, Kenjiro, Shirai, Tomoyuki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2000
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926232/
https://ncbi.nlm.nih.gov/pubmed/10744044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00859.x
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