Immunohistochemical Detection of Carcinogen‐DNA Adducts in Normal Human Prostate Tissues Transplanted into the Subcutis of Athymic Nude Mice: Results with 2‐Amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP) and 3,2′‐Dimethyl‐4‐aminobiphenyl (DMAB) and Relation to Cytochrome P450s and N‐Acetyltransferase Activity

Human prostate tissue transplanted into nude mice was examined immunohistochemically for DNA adducts formed after administration of 3,2′‐dimethyl‐4‐aminobiphenyl (DMAB) or 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP). Positive staining for DMAB‐ or PhIP‐DNA adducts was evident in 70–95% of...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Cui, Lin, Takahashi, Satoru, Tada, Mariko, Kato, Koji, Yamada, Yasuyuki, Kohri, Kenjiro, Shirai, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2000
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926232/
https://ncbi.nlm.nih.gov/pubmed/10744044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00859.x
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