Immunohistochemical Detection of Carcinogen‐DNA Adducts in Normal Human Prostate Tissues Transplanted into the Subcutis of Athymic Nude Mice: Results with 2‐Amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP) and 3,2′‐Dimethyl‐4‐aminobiphenyl (DMAB) and Relation to Cytochrome P450s and N‐Acetyltransferase Activity

Human prostate tissue transplanted into nude mice was examined immunohistochemically for DNA adducts formed after administration of 3,2′‐dimethyl‐4‐aminobiphenyl (DMAB) or 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP). Positive staining for DMAB‐ or PhIP‐DNA adducts was evident in 70–95% of...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Jpn J Cancer Res
المؤلفون الرئيسيون: Cui, Lin, Takahashi, Satoru, Tada, Mariko, Kato, Koji, Yamada, Yasuyuki, Kohri, Kenjiro, Shirai, Tomoyuki
التنسيق: Artigo
اللغة:Inglês
منشور في: Blackwell Publishing Ltd 2000
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926232/
https://ncbi.nlm.nih.gov/pubmed/10744044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00859.x
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