Adenovirus‐mediated Gene Transduction of IkB or IkB Plus Bax Gene Drastically Enhances Tumor Necrosis Factor (TNF)‐induced Apoptosis in Human Gliomas

Tumor necrosis factor‐α (TNF), which was initially supposed to be a promising cancer therapeutic reagent, does not kill most types of cancer cells partly due to the activation of an anti‐apoptotic gene, NF‐kB. NF‐kB forms an inactive complex with the inhibitor kappa B alpha (IkBα), which is rapidly...

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Vydáno v:Jpn J Cancer Res
Hlavní autoři: Shinoura, Nobusada, Yamamoto, Naoki, Yoshida, Yoko, Fujita, Takashi, Saito, Nobuto, Asai, Akio, Kirino, Takaaki, Hamada, Hirofumi
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2000
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926230/
https://ncbi.nlm.nih.gov/pubmed/10744043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00858.x
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