Dihydropyrimidine Dehydrogenase and Messenger RNA Levels in Gastric Cancer: Possible Predictor for Sensitivity to 5‐Fluorouracil

We investigated the correlation between tumor sensitivity to 5‐fluorouracil (5‐FU) and enzymatic activities of thymidylate synthetase (TS) and dihydropyrimidine dehydrogenase (DPD) in human gastric cancer specimens. Forty‐one patients with advanced gastric cancer gave informed consent and were enrol...

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Détails bibliographiques
Publié dans:Jpn J Cancer Res
Auteurs principaux: Ishikawa, Yoichiro, Kubota, Tetsuro, Otani, Yoshihide, Watanabe, Masahiko, Teramoto, Tatsuo, Kumai, Koichiro, Takechi, Teiji, Okabe, Hiroyuki, Fukushima, Masakazu, Kitajima, Masaki
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2000
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926227/
https://ncbi.nlm.nih.gov/pubmed/10744051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00866.x
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