Chemopreventive Effect of N‐(2‐Cyclohexyloxy‐4‐nitrophenyl)methane Sulfonamide (NS‐398), a Selective Cyclooxygenase‐2 Inhibitor, in Rat Colon Carcinogenesis Induced by Azoxymethane

Non‐steroidal anti‐inflammatory drugs (NSAIDs) such as sulindac and indomethacin inhibit colon carcinogenesis, and selective cyclooxygenase (COX)‐2 inhibitors are considered to be potential chemopreventive agents without the side effects of usual NSAIDs. We reported that NS‐398, N‐(2‐cyclohexyloxy‐4...

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Bibliographic Details
Published in:Jpn J Cancer Res
Main Authors: Yoshimi, Naoki, Shimizu, Masahito, Matsunaga, Kengo, Yamada, Yasuhiro, Fujii, Keiko, Hara, Akira, Mori, Hideki
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 1999
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926081/
https://ncbi.nlm.nih.gov/pubmed/10363578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00762.x
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